High on Lifeis the next title from Squanch Games, a company that Justin Roiland helped create back in 2016. These games tend to be sillier, often poking fun at the fabric of this industry. For better or worse, it’s easy to call these gamesRick and Morty-likes since the humor is so close to that cartoon and Roiland helped co-create that series. They’re the roguelikes of the comedy gaming universe.

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High on Lifeis a shooter that follows the exploits of a random hero swept up into an intergalactic syndicate. They must work together with Kenny, a sentient gun, to save Earth from becoming a drug zone. It’s a wild story, but an easy-to-pick-up shooter with these tips in mind.

8Use Headphones

The main reason to play this game is for the humor and not the challenge, so the Story level of difficulty is recommended. There is a way to turn down thechatter of the enemiesand the guns in the menu, but players should refrain from doing that.

It may get a bit much at times, but there’s a lot of good dialogue inHigh on Lifetoo. That’s why it is important to wear headphones. This will help clue players in on where enemies are coming from too.

Talking to an NPC in High on Life

7Who To Fight First

The first mission will have players go after a mob boss by thename of 9-Torg. After that players get to choose between two new bounties: Krubis and Douglas. One bounty is not stronger than the other but they each have benefits in the form of new guns that players should be aware of.

Defeating Douglas will grant playersaccess to Sweezywho acts a lot like the Needler from theHaloseries. Defeating Krubis will net players Gus who is like the shotgun of the game and is the better of the two choices for now.

Krubis in High on Life

6Yes, You Can Watch Tammy And The T-Rex

Tammy and the T-Rexis a classic cult movie of thegood but bad variety. Those familiar withRed Letter Mediawill know exactly why this movie is worth watching. It can be viewed in its entirety at the player’s house.

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That’s not the only weird movie players can watch either. The second movie to get unlocked will beBlood Harvestfollowed byVampire Hookers. Watching these three movies in High on Life is not the best way to experience them, but it’s good to know it is possible.

5Use The Environment To Your Advantage

High on Lifeis set up like an arena shooter wherein monsters will pop out of designated areas. Each arena will be open and full of things to aid players, which they should take advantage of. There will be grapple points, for example, which allow players to zip around the battlefield.

There are also exploding barrels to hit or caged creatures that will attack enemies too. It is reminiscent ofShadow Warrior 3, which is the closest and most recent shooter example.

Watching Tammy and The T-rex in High on Life

4Take Your Time

At its core, this game is a shooter and one with a sound control scheme. However, it’s also a comedy game and wants players to soak in the world. Don’t playHigh on Lifelike an ordinary shooter, going from one bounty to the next at breakneck speeds.

Take the time to talk to NPCs, look at posters, watch things on monitors, and so on. Not all of the humor will land like the weapon chatter but there is plenty of good stuff too. The ability to watch those cult classics movies is one example.

Fighting enemies in High on Life

3Upgrade Preferences

There is a central shop where players will go back to often on the main planet. Every time players unlock a gun, the store will get new inventory for weapon upgrades. The most important upgrade for all four guns is increasing ammo capacity which is a good upgrade to havein most shooters. Reducing the cooldown for the secondary fire is also a good upgrade for most weapons.

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Exploring the world in High on Life

If players do choose the Story difficulty, health upgrades will not be necessary. They are recommended if players choose to play High on Life on any other difficulty though. Overall, don’t spend every cent in the main store as other planets will have pop-up shops with missable upgrades.

2Take Notes

High on Lifeis not quite a Metroidvania, but it does have elements of one. Every gun in the game has a secondary fire option. Kenny can knock over certain platforms, Gus can shoot a blade that can be jumped on, and so on. Knifey, the melee weapon of the game,can unlock chests.

Whenever some sort of barrier prevents players from passing, make a note of that. There is no map in the game, making backtracking a tricky business. That’s why taking notes is more important than ever.

A shop in High on Life

1Never Go Back To Your House

Players will unlock an ability to warp back to the house on either Douglas’, or Krubis’ mission. Do not take advantage of this new portal even if it is tempting to go purchase some new upgrades before the boss fight. Players will not be able to return to this portal door the next time they go back.

Progress will be saved in the mission, but players have to start at the beginning of the stage. Eventually, there will be a way to warp to specific spots on each planet but that is a mechanic unlocked toward the end.

Exploring the world in High on Life

High on Lifewas released on July 11, 2025, and is available on PC, Xbox One, and Xbox Series X.

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A cutscene featuring characters in High on Life